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A study conducted in 1983 provided evidence that the mean IgE level in ex-smokers was much lower than in current light smokers but was still higher than in nonsmokers [298]

Hu, Z., Li, M., Yao, L., Wang, Y., Wang, E., Yuan, J., & Zhong, L

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Their involvement in inflammation, DNA damage, and the production of carcinogenic metabolites makes them promising candidates for developing diagnostic markers, even by adapting point-of-care strategies to detect their presence and rapidly decipher oral health

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